# TGF-β signaling in diseases

**Type:** Topics  
**Canonical URL:** https://picoportal.org/library/topics/tgf-signaling-in-diseases/

## Facts

| Field | Value |
| --- | --- |
| Citations | 1,189,158 |
| Description | This cluster of papers explores the diverse aspects of the Transforming Growth Factor Beta (TGF-ß) signaling pathway, including its role in Smad-dependent and Smad-independent pathways, tumor suppression, cancer progression, bone morphogenetic protein (BMP) signaling, immune response modulation, cell differentiation, metastasis, regulation of epithelial-mesenchymal transition (EMT), and angiogenesis. It also discusses the development and use of TGF-ß inhibitors for potential therapeutic interventions. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | https://openalex.org/T11501 |
| Works | 42,823 |

## Topic researchers

Showing 12 of 20.

- [Douglas G. Altman](https://picoportal.org/library/researchers/douglas-g-altman/)
- [Eric S. Lander](https://picoportal.org/library/researchers/eric-s-lander/)
- [Bert Vogelstein](https://picoportal.org/library/researchers/bert-vogelstein/)
- [Gad Getz](https://picoportal.org/library/researchers/gad-getz/)
- [Cyrus Cooper](https://picoportal.org/library/researchers/cyrus-cooper/)
- [Giuseppe Remuzzi](https://picoportal.org/library/researchers/giuseppe-remuzzi/)
- [Robert A. Weinberg](https://picoportal.org/library/researchers/robert-a-weinberg/)
- [Todd R. Golub](https://picoportal.org/library/researchers/todd-r-golub/)
- [Michael Karin](https://picoportal.org/library/researchers/michael-karin/)
- [Gordon B. Mills](https://picoportal.org/library/researchers/gordon-b-mills/)
- [Kenneth W. Kinzler](https://picoportal.org/library/researchers/kenneth-w-kinzler/)
- [André G. Uitterlinden](https://picoportal.org/library/researchers/andre-g-uitterlinden/)

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Source: PICO Portal — public research metadata, principally OpenAlex. See https://picoportal.org/library/sources/ for provenance and https://picoportal.org/library/methodology/ for what these figures mean.