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Protease and Inhibitor Mechanisms

TopicLeading institutions, researchers & key papers

Protease and Inhibitor Mechanisms is a topic indexed in PICO Portal from OpenAlex.

What is known about Protease and Inhibitor Mechanisms?

PICO Portalrecord summary

This cluster of papers explores the multifaceted roles of matrix metalloproteinases (MMPs) in cancer progression, angiogenesis, inflammation regulation, and extracellular matrix remodeling. It also delves into the potential of MMPs as therapeutic targets for cancer therapy and their involvement in various physiological processes such as cell signaling and tissue remodeling.

How many works does Protease and Inhibitor Mechanisms have?

PICO Portalindexed works

Protease and Inhibitor Mechanisms has 194 works in the PICO Portal index. The count is the OpenAlex total, not the number of papers listed on this page.

What is the OpenAlex record for Protease and Inhibitor Mechanisms?

PICO Portalopenalex

The OpenAlex for Protease and Inhibitor Mechanisms is on the source record.

What are the most-cited papers on Protease and Inhibitor Mechanisms?

PICO Portalmost cited works
IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion
Vasilena Gocheva, Hao‐Wei Wang, Bedrick B. Gadea, Tanaya Shree, Karen E. Hunter, Alfred L. Garfall, Tara Berman, Johanna A. Joyce
Genes & Development. 2010743 CitationsOPEN ACCESS
92-kD type IV collagenase mediates invasion of human cytotrophoblasts.
Clifford Librach, Zena Werb, Marilyn L. Fitzgerald, Kuan‐Ming Chiu, Norman Corwin, R A Esteves, Damian Grobelny, Richard E. Galardy, C H Damsky, S.J. Fisher
The Journal of Cell Biology. 1991722 CitationsOPEN ACCESS
Matrix Metalloproteinase 9 and Vascular Endothelial Growth Factor Are Essential for Osteoclast Recruitment into Developing Long Bones
Michael T. Engsig, Qingjun Chen, Thiennu H. Vu, Anne-Cecilie Pedersen, Bente Therkidsen, Leif R. Lund, Kim Henriksen, Thomas Lenhard, Niels T. Foged, Zena Werb, Jean‐Marie Delaissé
The Journal of Cell Biology. 2000597 CitationsOPEN ACCESS
Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer
Tanaya Shree, Oakley C. Olson, Benelita T. Elie, Jemila C. Kester, Alfred L. Garfall, Kenishana Simpson, Katherine M. Bell‐McGuinn, Emily C. Zabor, Edi Brogi, Johanna A. Joyce
Genes & Development. 2011538 CitationsOPEN ACCESS
The Type I Collagen Fragments ICTP and CTX Reveal Distinct Enzymatic Pathways of Bone Collagen Degradation
Patrick Garnero, Mercedes Ferreras, M.A. Karsdal, Róisı́n NicAmhlaoibh, Juha Risteli, Olivier Borel, Per Qvist, PD Delmas, NT Foged, Jean‐Marie Delaissé
Journal of Bone and Mineral Research. 2003476 CitationsOPEN ACCESS

Where is Protease and Inhibitor Mechanisms research published, and who funds it?

PICO Portalvenues & funding sources

TOP FUNDERS

National Science Foundation—
NIH—
Wellcome Trust—
European Research Council—
Funder breakdown is a member featureSign up free to unlock

How much of the research on Protease and Inhibitor Mechanisms is open access?

PICO Portalopen access share
73%OPEN ACCESS
Gold
20%
Green
13%
Hybrid
0%
Bronze
40%
Closed
27%

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