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Drug Transport and Resistance Mechanisms

TopicLeading institutions, researchers & key papers

Drug Transport and Resistance Mechanisms is a topic indexed in PICO Portal from OpenAlex.

What is known about Drug Transport and Resistance Mechanisms?

PICO Portalrecord summary

This cluster of papers explores the mechanisms of multidrug resistance in cancer, focusing on the role of ATP-dependent transporters, P-glycoprotein, bile acids, ABC transporters, and drug efflux pumps. It also delves into the involvement of nuclear receptors, metabolic regulation, and the impact on intestinal barrier function.

How many works does Drug Transport and Resistance Mechanisms have?

PICO Portalindexed works

Drug Transport and Resistance Mechanisms has 307 works in the PICO Portal index. The count is the OpenAlex total, not the number of papers listed on this page.

What is the OpenAlex record for Drug Transport and Resistance Mechanisms?

PICO Portalopenalex

The OpenAlex for Drug Transport and Resistance Mechanisms is on the source record.

What are the most-cited papers on Drug Transport and Resistance Mechanisms?

PICO Portalmost cited works
Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis
Wei Jia, Wei Jia, Guoxiang Xie, Weiping Jia, Weiping Jia
Nature Reviews Gastroenterology & Hepatology. 20171,907 CitationsOPEN ACCESS
Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
Jasper Smit, Alfred H. Schinkel, Ronald P.J. Oude Elferink, Albert K. Groen, Els Wagenaar, Liesbeth van Deemter, Carla A.A.M. Mol, R. Ottenhoff, Nathalie M. T. van der Lugt, Marian A. van Roon, Martin A. van der Valk, G. J. A. Offerhaus, Anton Berns, Piet Borst
Cell. 19931,468 Citations
Bile acids and the gut microbiota: metabolic interactions and impacts on disease
Stephanie L. Collins, Jonathan G. Stine, Jordan E. Bisanz, C. Denise Okafor, Andrew D. Patterson
Nature Reviews Microbiology. 20221,123 Citations
Cholesterol gallstone disease
Piero Portincasa, Antonio Moschetta, Giuseppe Palasciano
The Lancet. 2006761 Citations
Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity
Fei Li, Changtao Jiang, Kristopher W. Krausz, Yunfei Li, István Albert, Haiping Hao, Kristin Fabre, James B. Mitchell, Andrew D. Patterson, Frank J. Gonzalez
Nature Communications. 2013697 CitationsOPEN ACCESS

Where is Drug Transport and Resistance Mechanisms research published, and who funds it?

PICO Portalvenues & funding sources

TOP FUNDERS

National Science Foundation—
NIH—
Wellcome Trust—
European Research Council—
Funder breakdown is a member featureSign up free to unlock

How much of the research on Drug Transport and Resistance Mechanisms is open access?

PICO Portalopen access share
47%OPEN ACCESS
Gold
7%
Green
7%
Hybrid
7%
Bronze
27%
Closed
53%

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