# The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

**Type:** Papers  
**Canonical URL:** https://picoportal.org/library/papers/the-evolution-of-phosphatidylinositol-3-kinases-as-regulators-of-growth-and/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jeffrey A. Engelman,Ji Luo,Lewis C. Cantley |
| Citations | 3,323 |
| DOI | 10.1038/nrg1879 |
| Fields | Biochemistry, Genetics and Molecular Biology |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2009886463 |
| PMID | 16847462 |
| Type | article |
| Year | 2006 |

## Paper authors

- [Jeffrey A. Engelman](https://picoportal.org/library/researchers/jeffrey-a-engelman/)
- [Ji Luo](https://picoportal.org/library/researchers/ji-luo/)
- [Lewis C. Cantley](https://picoportal.org/library/researchers/lewis-c-cantley/)

## Paper journal

- [Nature Reviews Genetics](https://picoportal.org/library/journals/nature-reviews-genetics/)

## Paper primary topic

- [PI3K/AKT/mTOR signaling in cancer](https://picoportal.org/library/topics/pi3k-akt-mtor-signaling-in-cancer/)

## Paper topics

- [PI3K/AKT/mTOR signaling in cancer](https://picoportal.org/library/topics/pi3k-akt-mtor-signaling-in-cancer/)
- [Cellular transport and secretion](https://picoportal.org/library/topics/cellular-transport-and-secretion/)
- [Protein Kinase Regulation and GTPase Signaling](https://picoportal.org/library/topics/protein-kinase-regulation-and-gtpase-signaling/)

---
Source: PICO Portal — public research metadata, principally OpenAlex. See https://picoportal.org/library/sources/ for provenance and https://picoportal.org/library/methodology/ for what these figures mean.