# Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function

**Type:** Papers  
**Canonical URL:** https://picoportal.org/library/papers/phosphodiesterase-5-inhibition-augments-endogenous-antitumor-immunity-by/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Paolo Serafini,Kristen F. Meckel,Michael J. Kelso,Kimberly Noonan,Joseph A. Califano,Wayne M. Koch,Luigi Dolcetti,Vincenzo Bronte,Ivan Borrello |
| Citations | 757 |
| DOI | 10.1084/jem.20061104 |
| Fields | Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://rupress.org/jem/article-pdf/203/12/2691/1723424/jem_20061104.pdf |
| OpenAlex ID | https://openalex.org/W2120539661 |
| PMID | 17101732 |
| Type | article |
| Year | 2006 |

## Paper authors

- [Joseph A. Califano](https://picoportal.org/library/researchers/joseph-a-califano/)
- [Wayne M. Koch](https://picoportal.org/library/researchers/wayne-m-koch/)
- [Vincenzo Bronte](https://picoportal.org/library/researchers/vincenzo-bronte/)
- [Ivan Borrello](https://picoportal.org/library/researchers/ivan-borrello/)

## Paper journal

- [The Journal of Experimental Medicine](https://picoportal.org/library/journals/the-journal-of-experimental-medicine/)

## Paper primary topic

- [Phosphodiesterase function and regulation](https://picoportal.org/library/topics/phosphodiesterase-function-and-regulation/)

## Paper topics

- [Phosphodiesterase function and regulation](https://picoportal.org/library/topics/phosphodiesterase-function-and-regulation/)
- [Chemokine receptors and signaling](https://picoportal.org/library/topics/chemokine-receptors-and-signaling/)
- [Immunotherapy and Immune Responses](https://picoportal.org/library/topics/immunotherapy-and-immune-responses/)

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Source: PICO Portal — public research metadata, principally OpenAlex. See https://picoportal.org/library/sources/ for provenance and https://picoportal.org/library/methodology/ for what these figures mean.