# Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

**Type:** Papers  
**Canonical URL:** https://picoportal.org/library/papers/homozygous-disruption-of-the-murine-mdr2-p-glycoprotein-gene-leads-to-a-complete/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jasper Smit,Alfred H. Schinkel,Ronald P.J. Oude Elferink,Albert K. Groen,Els Wagenaar,Liesbeth van Deemter,Carla A.A.M. Mol,R. Ottenhoff,Nathalie M. T. van der Lugt,Marian A. van Roon,Martin A. van der Valk,G. J. A. Offerhaus,Anton Berns,Piet Borst |
| Citations | 1,468 |
| DOI | 10.1016/0092-8674(93)90380-9 |
| Fields | Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2172134989 |
| PMID | 8106172 |
| Type | article |
| Year | 1993 |

## Paper authors

- [Albert K. Groen](https://picoportal.org/library/researchers/albert-k-groen/)
- [Anton Berns](https://picoportal.org/library/researchers/anton-berns/)
- [Ronald P.J. Oude Elferink](https://picoportal.org/library/researchers/ronald-p-j-oude-elferink/)
- [Alfred H. Schinkel](https://picoportal.org/library/researchers/alfred-h-schinkel/)
- [Els Wagenaar](https://picoportal.org/library/researchers/els-wagenaar/)
- [Piet Borst](https://picoportal.org/library/researchers/piet-borst/)

## Paper journal

- [Cell](https://picoportal.org/library/journals/cell/)

## Paper primary topic

- [Drug Transport and Resistance Mechanisms](https://picoportal.org/library/topics/drug-transport-and-resistance-mechanisms/)

## Paper topics

- [Drug Transport and Resistance Mechanisms](https://picoportal.org/library/topics/drug-transport-and-resistance-mechanisms/)
- [Pediatric Hepatobiliary Diseases and Treatments](https://picoportal.org/library/topics/pediatric-hepatobiliary-diseases-and-treatments/)
- [Pharmacological Effects and Toxicity Studies](https://picoportal.org/library/topics/pharmacological-effects-and-toxicity-studies/)

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Source: PICO Portal — public research metadata, principally OpenAlex. See https://picoportal.org/library/sources/ for provenance and https://picoportal.org/library/methodology/ for what these figures mean.