# EGFR-Mediated Reactivation of MAPK Signaling Contributes to Insensitivity of <i>BRAF</i> -Mutant Colorectal Cancers to RAF Inhibition with Vemurafenib

**Type:** Papers  
**Canonical URL:** https://picoportal.org/library/papers/egfr-mediated-reactivation-of-mapk-signaling-contributes-to-insensitivity-of-i/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Ryan B. Corcoran,Hiromichi Ebi,Alexa B. Turke,Erin M. Coffee,Michiya Nishino,Alexandria P. Cogdill,Ronald D. Brown,Patricia Della Pelle,Dora Dias‐Santagata,Kenneth E. Hung,Keith T. Flaherty,Adriano Piris,Jennifer A. Wargo,Jeffrey Settleman,Mari Mino–Kenudson,Jeffrey A. Engelman |
| Citations | 1,032 |
| DOI | 10.1158/2159-8290.cd-11-0341 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://cancerdiscovery.aacrjournals.org/content/candisc/2/3/227.full.pdf |
| OpenAlex ID | https://openalex.org/W2110682589 |
| PMID | 22448344 |
| Type | article |
| Year | 2012 |

## Paper authors

- [Ryan B. Corcoran](https://picoportal.org/library/researchers/ryan-b-corcoran/)
- [Keith T. Flaherty](https://picoportal.org/library/researchers/keith-t-flaherty/)
- [Alexandria P. Cogdill](https://picoportal.org/library/researchers/alexandria-p-cogdill/)
- [Jennifer A. Wargo](https://picoportal.org/library/researchers/jennifer-a-wargo/)
- [Mari Mino–Kenudson](https://picoportal.org/library/researchers/mari-mino-kenudson/)
- [Dora Dias‐Santagata](https://picoportal.org/library/researchers/dora-dias-santagata/)
- [Jeffrey Settleman](https://picoportal.org/library/researchers/jeffrey-settleman/)
- [Hiromichi Ebi](https://picoportal.org/library/researchers/hiromichi-ebi/)
- [Jeffrey A. Engelman](https://picoportal.org/library/researchers/jeffrey-a-engelman/)

## Paper journal

- [Cancer Discovery](https://picoportal.org/library/journals/cancer-discovery/)

## Paper primary topic

- [Melanoma and MAPK Pathways](https://picoportal.org/library/topics/melanoma-and-mapk-pathways/)

## Paper topics

- [Melanoma and MAPK Pathways](https://picoportal.org/library/topics/melanoma-and-mapk-pathways/)
- [Colorectal Cancer Treatments and Studies](https://picoportal.org/library/topics/colorectal-cancer-treatments-and-studies/)
- [Cutaneous Melanoma Detection and Management](https://picoportal.org/library/topics/cutaneous-melanoma-detection-and-management/)

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Source: PICO Portal — public research metadata, principally OpenAlex. See https://picoportal.org/library/sources/ for provenance and https://picoportal.org/library/methodology/ for what these figures mean.