# Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

**Type:** Papers  
**Canonical URL:** https://picoportal.org/library/papers/dissecting-the-multicellular-ecosystem-of-metastatic-melanoma-by-single-cell-rna/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Itay Tirosh,Benjamin Izar,Sanjay M. Prakadan,Marc H. Wadsworth,Daniel J. Treacy,John J. Trombetta,Asaf Rotem,Christopher Rodman,Christine G. Lian,Gëorge F. Murphy,Mohammad Fallahi‐Sichani,Ken Dutton‐Regester,Jia‐Ren Lin,Ofir Cohen,Parin Shah,Diana Lu,Alex S. Genshaft,Travis K. Hughes,Carly G.K. Ziegler,Samuel W. Kazer,Aleth Gaillard,Kellie E. Kolb,Alexandra–Chloé Villani,Cory M. Johannessen,Aleksandr Andreev,Eliezer M. Van Allen,Monica M. Bertagnolli,Peter K. Sorger,Ryan J. Sullivan,Keith T. Flaherty,Dennie T. Frederick,Judit Jané‐Valbuena,Charles H. Yoon,Orit Rozenblatt–Rosen,Alex K. Shalek,Aviv Regev,Levi A. Garraway |
| Citations | 5,358 |
| DOI | 10.1126/science.aad0501 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://science.sciencemag.org/content/sci/352/6282/189.full.pdf |
| OpenAlex ID | https://openalex.org/W2332292689 |
| PMID | 27124452 |
| Type | article |
| Year | 2016 |

## Paper authors

Showing 10 of 19.

- [Itay Tirosh](https://picoportal.org/library/researchers/itay-tirosh/)
- [Ryan J. Sullivan](https://picoportal.org/library/researchers/ryan-j-sullivan/)
- [Monica M. Bertagnolli](https://picoportal.org/library/researchers/monica-m-bertagnolli/)
- [Gëorge F. Murphy](https://picoportal.org/library/researchers/george-f-murphy/)
- [Cory M. Johannessen](https://picoportal.org/library/researchers/cory-m-johannessen/)
- [Keith T. Flaherty](https://picoportal.org/library/researchers/keith-t-flaherty/)
- [Ken Dutton‐Regester](https://picoportal.org/library/researchers/ken-dutton-regester/)
- [Eliezer M. Van Allen](https://picoportal.org/library/researchers/eliezer-m-van-allen/)
- [Dennie T. Frederick](https://picoportal.org/library/researchers/dennie-t-frederick/)
- [Alexandra–Chloé Villani](https://picoportal.org/library/researchers/alexandra-chloe-villani/)

## Paper journal

- [Science](https://picoportal.org/library/journals/science/)

## Paper primary topic

- [CAR-T cell therapy research](https://picoportal.org/library/topics/car-t-cell-therapy-research/)

## Paper topics

- [CAR-T cell therapy research](https://picoportal.org/library/topics/car-t-cell-therapy-research/)
- [Cancer Immunotherapy and Biomarkers](https://picoportal.org/library/topics/cancer-immunotherapy-and-biomarkers/)
- [Single-cell and spatial transcriptomics](https://picoportal.org/library/topics/single-cell-and-spatial-transcriptomics/)

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Source: PICO Portal — public research metadata, principally OpenAlex. See https://picoportal.org/library/sources/ for provenance and https://picoportal.org/library/methodology/ for what these figures mean.