# Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells

**Type:** Papers  
**Canonical URL:** https://picoportal.org/library/papers/cancer-slc6a6-mediated-taurine-uptake-transactivates-immune-checkpoint-genes-and/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Tianyu Cao,Wenyao Zhang,Qi Wang,Chen Wang,Wanqi Ma,Cangang Zhang,Minghui Ge,Miaomiao Tian,Jia Yu,Anjun Jiao,Liang Wang,Manjiao Liu,Pei Wang,Zhiyu Guo,Yun Zhou,Shuyi Chen,Wen Yin,Jing Yi,Hao Guo,Hua Han,Baojun Zhang,Kaichun Wu,Daiming Fan,Xin Wang,Yongzhan Nie,Yuanyuan Lu,Xiaodi Zhao |
| Citations | 208 |
| DOI | 10.1016/j.cell.2024.03.011 |
| Fields | Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W4393386180 |
| PMID | 38565142 |
| Type | article |
| Year | 2024 |

## Paper authors

- [Kaichun Wu](https://picoportal.org/library/researchers/kaichun-wu/)
- [Xin Wang](https://picoportal.org/library/researchers/xin-wang-4/)
- [Chen Wang](https://picoportal.org/library/researchers/chen-wang-3/)
- [Liang Wang](https://picoportal.org/library/researchers/liang-wang-4/)
- [Daiming Fan](https://picoportal.org/library/researchers/daiming-fan/)
- [Yongzhan Nie](https://picoportal.org/library/researchers/yongzhan-nie/)

## Paper journal

- [Cell](https://picoportal.org/library/journals/cell/)

## Paper primary topic

- [Immune Cell Function and Interaction](https://picoportal.org/library/topics/immune-cell-function-and-interaction/)

## Paper topics

- [Immune Cell Function and Interaction](https://picoportal.org/library/topics/immune-cell-function-and-interaction/)
- [Aldose Reductase and Taurine](https://picoportal.org/library/topics/aldose-reductase-and-taurine/)
- [Histone Deacetylase Inhibitors Research](https://picoportal.org/library/topics/histone-deacetylase-inhibitors-research/)

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Source: PICO Portal — public research metadata, principally OpenAlex. See https://picoportal.org/library/sources/ for provenance and https://picoportal.org/library/methodology/ for what these figures mean.