# BRAF mutation predicts sensitivity to MEK inhibition

**Type:** Papers  
**Canonical URL:** https://picoportal.org/library/papers/braf-mutation-predicts-sensitivity-to-mek-inhibition/

## Facts

| Field | Value |
| --- | --- |
| Author Names | David B. Solit,Levi A. Garraway,Christine A. Pratilas,Ayana Sawai,Gad Getz,Andrea Basso,Qing Ye,Jose Lobo,Yuhong She,Iman Osman,Todd R. Golub,Judith S. Sebolt–Leopold,William R. Sellers,Neal Rosen |
| Citations | 1,330 |
| DOI | 10.1038/nature04304 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/3306236 |
| OpenAlex ID | https://openalex.org/W2080686146 |
| PMID | 16273091 |
| Type | article |
| Year | 2005 |

## Paper authors

- [David B. Solit](https://picoportal.org/library/researchers/david-b-solit/)
- [Todd R. Golub](https://picoportal.org/library/researchers/todd-r-golub/)
- [Gad Getz](https://picoportal.org/library/researchers/gad-getz/)
- [Levi A. Garraway](https://picoportal.org/library/researchers/levi-a-garraway/)
- [William R. Sellers](https://picoportal.org/library/researchers/william-r-sellers/)
- [Christine A. Pratilas](https://picoportal.org/library/researchers/christine-a-pratilas/)
- [Iman Osman](https://picoportal.org/library/researchers/iman-osman/)
- [Neal Rosen](https://picoportal.org/library/researchers/neal-rosen/)

## Paper journal

- [Nature](https://picoportal.org/library/journals/nature/)

## Paper primary topic

- [Melanoma and MAPK Pathways](https://picoportal.org/library/topics/melanoma-and-mapk-pathways/)

## Paper topics

- [Melanoma and MAPK Pathways](https://picoportal.org/library/topics/melanoma-and-mapk-pathways/)
- [PI3K/AKT/mTOR signaling in cancer](https://picoportal.org/library/topics/pi3k-akt-mtor-signaling-in-cancer/)
- [Cancer Mechanisms and Therapy](https://picoportal.org/library/topics/cancer-mechanisms-and-therapy/)

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Source: PICO Portal — public research metadata, principally OpenAlex. See https://picoportal.org/library/sources/ for provenance and https://picoportal.org/library/methodology/ for what these figures mean.